Our Studies

Current Studies

MIRAGE

Effectiveness of iMIpenem-Relebactam for multidrug-resistant Pseudomonas AeruGinoa in pnEumonia and bloodstream infections in the United States

STEWARDS study ceftolozane tazobactam versus traditional agents for MDR Pseudomonas. STEWARDS trial

STEWARDS

Optimizing eScalation: CefTolozane/tazobactam vErsus treatment With trAditional anti-pseudomonal β-lactams foR pneumonia or blooDStream infections due to MDR P. aeruginosa

CONVINCE study cefiderocol versus ceftolozane tazobactam for MDR Pseudomonas. CONVINCE trial

CONVINCE

CefiderOcol treatmeNt Versus ceftolozane/tazobactam for the treatment of pneumonia and/or bloodstream INfeCtions due to multidrug-resistant PsEudomonas aeruginosa

CAMEL study of meropenem vaborbactam ceftazidime avibactam for carbapenem resistant Enterobacterales CRE. KPC Klebsiella. CAMEL trial.

CAMEL

Ceftazidime-Avibactam versus Meropenem-vaborbactam for the treatment of bloodstream infections and/or pneumonia due to carbapenem-resistant EnterobacteraLes

TUNDRA study of carbapenem resistant Acinetobacter baumannii CRAb CRAB  and sulbactam durlobactam use. TUNDRA trial. unasyn tetracyclines cefiderocol. SUL-DUR

TUNDRA

Management strategies for AcineTobacter baUmannii in the UNited States: Real-world evidence and clinical outcomes associated with Sulbactam-DuRlobActam

Upcoming Studies

Interested in Acinetobacter? Carbapenemases? Stenotrophomonas? Metallo-beta lactamases?

Check back soon to learn more.

Completed Studies

CACTUS

Ceftazidime-Avibactam versus Ceftolozane-Tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the United States

Our first CACTUS manuscript has been accepted by The Lancet Infectious Diseases!
Check back soon for a link to the finalized manuscript.

In the meantime, you check out our preprint
here.

Presentations & Publications

Upcoming Presentations

Please check back regularly for upcoming presentation information.


Past Presentations

IDWeek, Los Angeles, October 2024

Oral Presentations - CACTUS
Title: Defining the magnitude of desirability of outcome ranking (DOOR) differences in effectiveness of Ceftazidime-Avibactam (CZA) versus Ceftolozane-Tazobactam (C/T) for multidrug-resistant (MDR) Pseudomonas aeruginosa infections in the United States (CACTUS)
Presented by: Dr. Jason Pogue

Title: Impact of Patient Subgroups on the Efficacy of Ceftazidime-Avibactam (CZA) versus Ceftolozane-Tazobactam (C/T) for Multidrug-resistant (MDR) Pseudomonas aeruginosa infections in the United States (CACTUS)
Presented by: Dr. Michael Veve

Poster Presentation - MIRAGE
Title: Effectiveness of Imipenem-Relebactam for Multidrug-resistant Pseudomonas aeruginosa in Pneumonia and Bloodstream Infections in the United States (MIRAGE)
Session: Treatment of Challenging Gram-negative Infections

Dr. Jason Pogue presenting CACTUS DOOR analysis. CACTUS study. ceftolozane tazobactam ceftazidime avibactam. MDR Pseudomonas bloodstream and pneumonia
Dr. Michael Veve presenting CACTUS subgroup analysis. CACTUS study. ceftolozane tazobactam ceftazidime avibactam. MDR Pseudomonas bloodstream and pneumonia

34th ECCMID, Barcelona, April 2024

Oral Presentation - CACTUS
ECCMID 2024 Top Rated Abstract
Title: Time to clinical response among patients treated with ceftazidime-avibactam versus ceftolozane-tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the United States (CACTUS)
Presented by: Dr. Ryan Shields
Session: Management of infections caused by multi-drug resistant organisms: challenges and solutions

Attended ECCMID but missed the session? You can access the recording on your ECCMID Online Programme.

Poster Presentation - CACTUS
Title: Efficacy of ceftazidime-avibactam versus ceftolozane-tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the United States (CACTUS) among immunocompromised patients

Ryan Shields speaking. CACTUS study presentation. ECCMID 2024 Barcelona. CACTUS trial. ceftolzane tazobactam ceftazidime avibactam. MDR Pseudomonas bloodstream and pneumonia

IDWeek, Boston, October 2023

Oral Presentation - CACTUS
Title: A multicenter, observational study to compare the effectiveness of Ceftazidime-Avibactam versus Ceftolozane-Tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the United States (CACTUS)
Session: Treatment of Challenging Gram-negative Infections

Attended IDWeek but missed the session? You can access the recording on idweek.org.
Want to read the abstract? Access it
here.

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